11 results
diagnosis hematology management differential classification mds myelodysplastic approach celiac chronic cll cobalamin deficiency emergencies hemeonc hodgkins lymphocytic lymphoma myelodysplasia nutrition
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Leukemia, Tumour ... Megakaryopoiesis • B12
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... anemia Treatment ... #Anemia #oncology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Deficiency • B12 ... Deficiency • Aplastic ... of Chronic Disease ... #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute leukemia ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Chronic Myelogenous Leukemia ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... • Neutropenia, anemia ... Pure red cell aplasia ... #diagnosis #workup ... #oncology #hematology
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
- Diagnosis Algorithm ... Iron-deficiency anemia ... unresponsive to treatment ... without discernable cause ... #gastroenterology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Anemia • Aplastic ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... diagnosis #hematology #oncology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... wt loss • If anemia ... to IBD, celiac disease ... Check for IF ab Treatment ... diagnosis e.g. leukemia
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Hodgkin Lymphoma Workup ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology
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