31 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm Low ... Renal Disease, Liver ... (>100 fL) • B12 ... #MCV #Classification
Causes of Low Vitamin B12 Levels
Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people
Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... antagonists #VitaminB12 ... #deficiency #low ... #cobalamin #differential
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Volume (MCV) - Differential ... • Dietary Deficiency ... - Low Serum B12 ... and Folate Deficiency
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... • B12/Folate ... Deficiency • Aplastic ... #Classification ... Diagnosis #Algorithm #Causes
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Erythropoiesis (B12 ... in pernicious anemia ... Losses Non-renal ... vomiting) • Low
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Approach - MCV) Low ... Megaloblastic: Vitamin B12 ... deficiency • ... morphologic #mcv #differential ... #diagnosis #causes
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... , or folate deficiency ... • Hemolytic anemia ... • End-stage renal ... Diagnosis #DM2 #Differential
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... Alkalosis - Differential ... Chloridorrhea Renal ... • Penicillins Renal ... Syndrome • Enzyme deficiency
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
SIADH, Cortisol deficiency ... Primary polydipsia, Low ... solute intake, Renal ... hyponatremia #diagnosis #differential ... #algorithm #causes
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... neuropathy • Renal ... : - Renal failure