34 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... • Dietary Deficiency ... - Low Serum B12 ... • Small Bowel Disorder ... and Folate Deficiency
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm Low ... (>100 fL) • B12 ... #MCV #Classification ... #Differential #
Causes of Low Vitamin B12 Levels
Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people
Autoimmune
B12 Levels Low ... vitamin B12 intake ... antagonists #VitaminB12 ... #deficiency #low ... #cobalamin #differential
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... • B12/Folate ... Deficiency • Aplastic ... • RBC Membrane Disorder ... #Classification
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Algorithm - Iron deficiency ... disease - Vitamin B12 ... and/or folate deficiency ... Probable bone marrow disorder ... hematology #diagnosis #differential
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... - Coagulation disorder ... gestation • Vitamin B12 ... #Vitamins #Deficiency ... #differential #
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Approach - MCV) Low ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... deficiency • ... morphologic #mcv #differential
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Macrocytic RBC: Vitamin B12 ... or Folate deficiency ... Unstable hemoglobin disorders ... RBC #Morphology #differential
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
thiamine (vitamin B1 ... ) deficiency, commonly ... and retrograde amnesia ... #vitaminB1 #B1 # ... diagnosis #comparison #neurology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Erythropoiesis (B12 ... in pernicious anemia ... vomiting) • Low ... #low #potassium