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diagnosis algorithm causes mcv oncology acidosis aplastic approach atlas bloodcell elevation erythematosus hemolysis lactate lactic lupus macrocytic management microscopy morphology
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
• 812, Folate ... Deficiency • ... #differential # ... diagnosis #algorithm #hematology ... #workup
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Algorithm - Iron deficiency ... disease - Vitamin B12 ... Underproduction #Algorithm #hematology ... #diagnosis #differential ... #workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... , B12 deficiency ... Reticulocytosis, MDS ... MCV #Algorithm #Differential ... #Diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... (>100 fL) • B12 ... #MCV #Classification ... #Differential # ... Algorithm #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... • B12/Folate ... Deficiency • Aplastic ... #Classification ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Macrocytic RBC: Vitamin B12 ... Liver Disease, MDS ... RBC #Morphology #differential ... #diagnosis #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
formerly known as ... crisis • Severe B12 ... deficiency • Mechanical ... macroangiopathic hemolytic anemia ... #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... for workup, including ... Acute hemolysis, deficiency ... anemia, Rebound ... Matthew Ho, MD
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
to repair DNA, as ... , GATA2 deficiency ... , CTLA4 deficiency ... Hypocellular/Hypoplastic MDS ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology
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