24 results
diagnosis hematology algorithm management classification cobalamin hepatology mcv oncology spinal spinalcord syndromes vitaminb12 acidosis alkaline alp approach arteritis calculation cirrhosis
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... Nutritional deficiency ... : • B12/folate
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Pernicious Anemia ... - Low Serum B12 ... • Pernicious Anemia ... #Macrocytic #Anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... • B12/Folate ... Deficiency • Aplastic ... Anemia • Anemia ... Non-lmmune #Anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm Low ... Poisoning • Anemia ... Marrow Failure • Anemia ... (>100 fL) • B12
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Megakaryopoiesis • B12
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... and petechiae Causes ... may result from low
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... Approach - MCV) Low ... Megaloblastic: Vitamin B12 ... morphologic #mcv #differential ... #diagnosis #causes
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
approximately how ... loss), Vitamin B12 ... marrow failure: Aplastic ... anemia, Marrow ... #differential #
Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... vitamin B12 intake ... Autoimmune - Pernicious anaemia ... #differential #
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... autoantibodies (pernicious anemia ... Worsening macrocytic anemia ... wt loss • If anemia ... - CBC, PBS - anemia
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