33 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Dietary Deficiency ... Myelodysplastic Syndromes ... and Folate Deficiency ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Megaloblastic: Vitamin B12 ... deficiency • ... Myelodysplastic syndrome ... differential #diagnosis #causes ... #hematology
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
- Thiamine Deficiency ... thiamine (vitamin B1 ... and retrograde amnesia ... #vitaminB1 #B1 # ... diagnosis #comparison #neurology
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... Clinical Findings ... • Anterograde amnesia ... presentation of Thiamine deficiency ... #neurology #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
e.g AEIOU ) or anuria ... require urgent nephrology ... creatinine (in 12 ... KidneyInjury #simplified #workup ... #diagnosis #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... osmolarity If cause ... investigations depending on clinical ... Differential #Diagnosis #nephrology ... #causes
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Nutritional: DiabetesB12 deficiency ... , Uremia/ESRD, Hypothyroidism ... Paraprotein-associated (POEMS syndrome ... differential #diagnosis #causes ... #neurology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... a syndrome identical ... deficiency. ... The classic clinical ... of pernicious anemia