26 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Renal Disease, Liver ... (>100 fL) • B12 ... Deficiency • ... Folate Deficiency ... #MCV #Classification
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... #Vitamins #Deficiency
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
• Scleroderma renal ... crisis • Severe B12 ... deficiency • Mechanical ... macroangiopathic hemolytic anemia ... " • HELLP syndrome
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Erythropoiesis (B12 ... in pernicious anemia ... • Refeeding syndrome ... Medications Renal ... Losses Non-renal
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... Niacin, Vitamin D deficiency ... FEPO4 ≥ 5% - Renal ... Diagnosis #Framework #Workup ... #phosphate #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... investigations depending on clinical ... Abdominal compartment syndrome ... syndrome: troponin ... #Injury #AKI #Workup
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
- Thiamine Deficiency ... thiamine (vitamin B1 ... and retrograde amnesia ... #vitaminB1 #B1 # ... diagnosis #comparison #neurology
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... Clinical Findings ... • Anterograde amnesia ... presentation of Thiamine deficiency ... #neurology #diagnosis
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
1) Clinical ... Whipple, vitamin deficiency ... - Progressive amnesia ... Aphaso-apraxo-agnosia syndrome ... Differential #Subtypes #Classification
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... , GATA2 deficiency ... , CTLA4 deficiency ... - Parvovirus B19 ... • Parvovirus B19