14 results
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
inflammation) • Iron ... deficiency • ... Megaloblastic: Folate ... deficiency, B12 ... Differential #Diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Reticulocytes, MCV ... Iron, Ferritin, ... Deficiency • ... B12/Folate Deficiency ... Algorithm #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... Volume (<80 fL) • Iron ... (>100 fL) • B12 ... Folate Deficiency ... Algorithm #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Microcytic" • Iron ... deficiency • ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... diagnosis #causes #hematology
Iron Deficiency Anemia (IDA)
Tests:
 • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency ... : • MCV/RBC - ... #Deficiency #Anemia ... IDA #ferritin #Fe ... #diagnosis #hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Algorithm - Iron ... deficiency anemia ... disease - Vitamin B12 ... and/or folate deficiency ... Underproduction #Algorithm #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
TIBC increased - Fe ... • Iron Deficiency ... Malabsorption, Dietary Deficiency ... normal/decreased - Fe ... Algorithm #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Corpuscular Volume (MCV ... Neutrophils - Low RBC Folate ... • Dietary Deficiency ... and Folate Deficiency ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia ... Macrocytic RBC: Vitamin B12 ... or Folate deficiency ... deficiency anemia ... differential #diagnosis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
deficiencies: Iron ... loss), Vitamin B12 ... , Folate • Hormone ... , G6PD deficiency ... Production #Index #hematology