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diagnosis differential algorithm causes macrocytic classification aplastic approach atlas bloodcell calculation disease elevatedmcv index laboratory macrocytosis management mds microcytic microscopy
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Algorithm - Iron ... deficiency anemia ... disease - Vitamin B12 ... and/or folate deficiency ... Underproduction #Algorithm #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
inflammation) • Iron ... deficiency • ... Megaloblastic: Folate ... deficiency, B12 ... Differential #Diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Reticulocytes, MCV ... Iron, Ferritin, ... Deficiency • ... B12/Folate Deficiency ... Algorithm #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... Volume (<80 fL) • Iron ... (>100 fL) • B12 ... Folate Deficiency ... Algorithm #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron ... deficiency • ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... diagnosis #causes #hematology
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
• 812, Folate ... Deficiency • ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology ... #workup
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Corpuscular Volume (MCV ... Neutrophils - Low RBC Folate ... • Dietary Deficiency ... and Folate Deficiency ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia ... Macrocytic RBC: Vitamin B12 ... or Folate deficiency ... deficiency anemia ... differential #diagnosis #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
(cell) volume (MCV ... or B12 repletion ... substrate (e.g. iron ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Iron ... loss), Vitamin B12 ... , Folate • Hormone ... , G6PD deficiency ... Production #Index #hematology
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