8 results
diagnosis differential hematology algorithm causes classification pancytopenia bloodcell calculation index microscopy morphologic morphology neutropenia nomenclature production rbc red reticulocyte
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... inflammation) • Iron ... Megaloblastic: Folate ... deficiency, B12 ... Differential #Diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Reticulocytes, MCV ... Iron, Ferritin, ... Deficiency • ... B12/Folate Deficiency
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
(Morphological Approach ... Microcytic" • Iron ... Megaloblastic: Vitamin B12 ... deficiency, Folate ... diagnosis #causes #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... Volume (<80 fL) • Iron ... (>100 fL) • B12 ... Folate Deficiency ... #MCV #Classification
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • ... B12/folate/combined ... deficiencies
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
• Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... Deficiencies: ... consumption • Vitamin B12 ... • Folate deficiency
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia ... Macrocytic RBC: Vitamin B12 ... or Folate deficiency ... deficiency anemia ... #microscopy #atlas
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
: Iron deficiency ... loss), Vitamin B12 ... , Folate • Hormone ... deficiencies: Chronic ... , G6PD deficiency
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