43 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Chronic Bleed ... Deficiency • B12 ... Disease • Marrow ... Diagnosis #Algorithm #Causes ... #Hematology
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... neutrophils #AML #Clinical ... #Hematology #Pathology ... #Smear
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... : • Acute or Chronic ... disorders • Celiac disease ... effect following treatment ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Anemia of Chronic ... (>100 fL) • B12 ... Diagnosis #Algorithm #Causes ... #Hematology
Leukoerythroblastosis and myelophthisic anemia can be associated with any marrow-replacing process. In this case, the likely
In this case, the ... Leukoerythroblastosis #Hematology ... #Pathology #Smear ... #Microscopy #Clinical
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Aggressive disease ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Normal Blood Smear ... • Pancreatic Disease ... • Liver Disease ... #Hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
features in most cases ... leukemia #APL #APML #Pathology ... #Hematology #Clinical ... #Smear
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... → Refer to hematology ... Rebound effect from treatment ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
kidney disease, ... Megaloblastic: Vitamin B12 ... Alcohol use, Liver disease ... differential #diagnosis #causes ... #hematology