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diagnosis differential management anemia causes algorithm rheumatology syndrome pediatrics foam foamed photo sickle sicklecell sicklecellanemia sicklecelldisease sicklecells workup classification hemeonc
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) (e.g. lupus, CLL ... cold agglutin disease ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... differential #diagnosis #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
fragmentation hemolysis ... organ or stem cell ... crisis • Severe B12 ... differential #diagnosis #hematology ... #hemolysis
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm By Matthew Ho, MD PhD @MatthewHoMD #Diffuse
Diffuse large B cell ... Management and Treatment ... DLBCL #Management #Treatment ... #Algorithm #oncology ... #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
and non-hematologic ... malignancies • Infection ... Myelofibrosis Stem cell ... deficiency: • B12 ... Algorithm #Causes #Hematology
Treatments for Sickle Cell disease #Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
Treatments for Sickle ... Cell disease ... sicklecells #sickle #hematology ... #anemia #clinical
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Anemia (AIHA) Treatment ... esp if severe disease ... Polyclonal: - Infection ... #Anemia #AIHA #Treatment ... #management #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... Antibody-mediated hemolysis ... consumption • Vitamin B12 ... deficiency Infections ... Differential #Diagnosis #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
-100): • Non-hemolytic ... Macroangiopathic, Infections ... Folate deficiency, B12 ... Non-megaloblastic: Liver disease ... Differential #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... and RES-mediated hemolysis ... • Sickle cell ... circulation - Infections ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Diagnosis #Algorithm #hematology
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