131 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... thickening Signs ... and Symptoms: ... #diagnosis #signs ... #symptoms #testing
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... / Symptoms: - ... Xeroderma (Dry skin ... Sjogrens #Syndrome #Pathophysiology ... #Symptoms
COVID-19 Skin Rashes on Fingers and Toes

Please be aware there are skin signs of covid. Purple
COVID-19 Skin Rashes ... signs of covid. ... no other covid symptoms ... Fingers #Toes #Dermatology ... #Clinical #Pernio
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... oral ulcers in 12 ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... Pathogenesis and Clinical ... the etiology Signs ... GravesDisease #pathophysiology ... #signs #diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... bleeding disorder Clinical ... bruising • Skin ... factor VIII) Treatment ... #Diagnosis #Hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... trigger - Direct skin ... and duration of symptoms ... angioedema Other symptoms ... Urticaria #diagnosis #rheumatology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... in GBA1 gene Clinical ... #Diagnosis #Signs ... #Symptoms
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... : • Disease fatal ... neuropathies • Skin ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary