89 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelogenous Leukemia ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Cancer: • Leukemia ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
- Anemia of chronic ... disease - Vitamin ... B12 and/or folate ... Underproduction #Algorithm #hematology ... #diagnosis #differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... of Chronic Disease ... of Chronic Disease ... (>100 fL) • B12 ... Algorithm #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
disease, Acute ... Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... morphologic #mcv #differential ... diagnosis #causes #hematology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Diagnosis Chronic ... liver disease ( ... cirrhosis or chronic ... Fitz-Hugh-Curtis syndrome ... #Diagnosis #hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... heart failure (chronic ... (Budd-Chiari syndrome ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Reactive: • Anemia ... Myelofibrosis • Chronic ... Myeloid Leukemia ... causes #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... malignancies • Anemia ... Myelodysplastic syndrome ... myeloid leukemia ... Diagnosis #Causes #hematology