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diagnosis management differential algorithm lfts syndrome hepatitis dili hepatocellular hepatopulmonary indications aclf acute aih albumin autoimmune bariatric biliary bypass calling
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... disease, liver ... Injury (DILI) ... #Hepatology #gastroenterology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... • NAFLD • Cirrhosis ... injury) • Ischemic ... Differential #Diagnosis #hepatology ... #transaminitis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... CMV), Alcoholic cirrhosis ... #Injury #hepatology ... #LFTs #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury → liver ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... disease 6-9 mo ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... ) - 8g per liter ... • Acute kidney injury ... Indications #Management #Cirrhosis ... #treatment #hepatology
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
Gl History - Cirrhosis ... disease work up ... - Liver US ... Calling #Referral #Hepatology ... #Gastroenterology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... disease: > 2 ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology ... #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Venoocclusive disease ... disease: > 2 ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... involvement, Kidney injury ... non-essential drug/HDS treatments ... disease, Hepatic ... #Algorithm #hepatology
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