62 results
diagnosis differential algorithm causes management oncology rheumatology hemolysis cirrhosis clinical leukemia lupus mcv rbc thrombocytosis atlas hemeonc hepatitis hypertension liver
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Increased red cell ... #Hemolytic #Anemia ... Differential #Causes #Workup ... #Hematology #Diagnosis
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
of Chronic Disease ... • Bleeding • Hemolysis ... of Chronic Disease ... (>100 fL) • B12 ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Macrocytic RBC: Vitamin B12 ... Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... differential #diagnosis #hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
- Anemia of chronic ... disease - Vitamin ... B12 and/or folate ... Underproduction #Algorithm #hematology ... #differential #workup
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
organ or stem cell ... crisis • Severe B12 ... anemia" • HELLP ... differential #diagnosis #hematology ... #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... ) (e.g. lupus, CLL ... cold agglutin disease ... differential #diagnosis #hematology ... #anemia
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
• 812, Folate ... Hypothyroid • Liver Disease ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology ... #workup
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
loss), Vitamin B12 ... kidney disease, ... Microangiopathic hemolytic ... defects (e.g. sickle cell ... Production #Index #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Microangiopathic hemolytic ... Microspherocytes: Autoimmune hemolytic ... cells: Sickle cell ... disease Bite cells ... Smear #Analysis #hematology
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