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diagnosis rheumatology differential oncology sle aps erythematosus guidelines systemic algorithm anticoagulation cirrhosis eular2019 hepatopulmonary summary thrombosis acquired activation anemia aplastic
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Syndrome (APS) ... ): • Lupus anticoagulant ... to be present Treatment ... #Syndrome #APS ... #diagnosis #management
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS Venous Thrombosis - Arterial Thrombosis INR Target Duration Recurrence Dr. Laurent ARNAUD
thrombosis in (Antiphospholipid ... Syndrome) APS ... #Syndrome #APS ... #management #EULAR2019 ... #hematology #treatment
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... Wiskott-Aldrich syndrome ... : • Systemic lupus ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Chain deposition disease ... RA, Sjogren's), antiphospholipid ... syndrome, atheroembolic ... S - Systemic Lupus ... #differential #hematology
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS Previous Thrombosis? Previous Pregnancy Complications? Dr. Laurent ARNAUD @Lupusreference #obstetrics
in (Antiphospholipid ... Syndrome) APS ... #Syndrome #APS ... #guidelines #rheumatology ... #obgyn #treatment
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Human parvovirus B19 ... infection • Lyme disease ... reticularis • Antiphospholipid-antibody ... syndrome • Vasculitis ... lesions • Discoid lupus
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... (for secondary APS ... cerebritis #diagnosis #management ... #treatment
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... Treatment: • ... #Systemic #Lupus ... #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease ... #Summary #rheumatology
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