38 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... • Pancreatic Disease ... Myelodysplastic Syndromes ... • Liver Disease ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... PD deficiency, Pulmonary ... Hemolytic uremic syndrome ... key #diagnosis #differential ... #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
chronic kidney disease ... Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... morphologic #mcv #differential ... diagnosis #causes #hematology
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Pleural Effusion - Differential ... Malignancy • Pulmonary ... Collagen vascular disease ... Gastrointestinal disease ... • Asbestos • Uremia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
- Differential ... athletic training, Pulmonary ... Gastrectomy, WHDA syndrome ... Structural: Celiac disease ... Algorithm #ferritin #hematology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Chronic Obstructive Pulmonary ... Disease Neurologic ... Chronic Fatigue Syndrome
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... fraction < 20% Differential ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology