41 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Pancreatic Disease ... and Folate Deficiency ... • Liver Disease ... #Hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Erythematosus - Summary ... Antinuclear (ANA ... Treatment: • ... #Summary #diagnosis ... #rheumatology #
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Management Summary ... Workup: - ANA ... life-threatening • Treatment ... Evolution: Chronic disease ... #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... Splenomegaly - CTD (SLE ... Associated - SLE ... Differential #Diagnosis #hematology ... #rheumatology #
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Chronic Bleed - Any ... Deficiency • B12 ... Disease • Marrow ... Diagnosis #Algorithm #Causes ... #Hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
), RA, crystal disease ... Inflammatory, crystalline disease ... Like in this case ... Chronic = RA, SLE ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
PT, aPTT(liver disease ... function test, ANA ... (e.g., SLE), anti-phospholipid ... changes), high MCV anemia ... #Workup #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Management Summary ... old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... #hematology #oncology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... XR, MRI to dx and ... dz difficult to see ... #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Neurological 12% ... - Hemolytic anemia ... Auto-Antibodies: - ANA ... Lupusreference #SLE ... #differential #rheumatology