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management diagnosis sle druginduced erythematosus oncology systemic hcq hematology hydroxychloroquine medications syndrome toxicity adverseeffects anemia anthracycline aplastic behcets benefits capsulatum
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... autoantibodies that will cause ... Puncture, EEG Treatment ... CNS #neurology #rheumatology ... diagnosis #management #treatment
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
suspected) • In case ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Pharmacologic Treatment of Hypertensive Emergencies in Pregnancy Drug - Dose range - Onset/oeak/duration - Side effects -
Pharmacologic Treatment ... , tachycardia, nausea ... , hypotension, lupus-like ... - Urapidil - Nausea ... Obstetrics #OBGyn #HTN #Pharmacology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... comparison #table #rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... 0.5-0.7 g/g by 12 ... Nephritis #Management #treatment ... #management #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... rare with ~100 cases ... Risks #Benefits #Lupus ... #pharmacology # ... #sideeffects #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... by case) • Surgery ... #management #pharmacology ... #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Parvovirus B19 ... • Parvovirus B19 ... aplastic anemia Treatment ... Anemia #oncology #hematology
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
patients who have treatment-resistant ... elimination half-life of 12 ... Clozapine is known to cause ... Toxicity #Diagnosis #Pharmacology
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