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diagnosis management differential hematology anemia oncology sle algorithm classification dermatology disease erythematosus systemic thrombocytopenia antiphospholipid bowel druginduced ibs inflammatory irritable
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Puncture, EEG Treatment ... CNS #neurology #rheumatology ... diagnosis #management #treatment
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Wiskott-Aldrich syndrome ... Diseases: • Systemic lupus ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... diagnosis and treatment ... Inflammatory causes ... : • Susac syndrome ... • Systemic lupus
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... severe disease Treatment ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... Diagnosis #Algorithm #Causes ... #Hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... S - Systemic Lupus ... #differential #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Low Serum B12 ... Myelodysplastic Syndromes ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Myocarditis Infectious Etiologies: • Viral agents: Adenoviruses, Enteroviruses (coxsackievirus), Herpesviruses (human herpesvirus 6, Epstein—Barr virus),
Causes of Myocarditis ... A, Parvovirus B19 ... Immunological Syndromes ... Churg-Strauss syndrome ... Sarcoidosis, Systemic lupus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... comparison #table #rheumatology
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