12 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology #
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... life-threatening • Treatment ... Evolution: Chronic disease ... #lupus #Systemic ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... months to years) Systemic ... life-threatening • Treatment ... Evolution: Chronic disease ... comparison #table #rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... suspicion of severe disease ... guidelines General - Systemic ... Rheumatology ... #Limping #NWB #Algorithm
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... oral ulcers in 12 ... Oral aphthae : SLE ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
approach to kidney disease ... associated with systemic ... Non-LN Kidney Disease ... Nephritis #diagnosis #algorithm ... #sle #nephrology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Cryoglobulinemia (4%-12% ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
myelopathy - Vit B12 ... Sarcoidosis, Behcet disease ... - SLE, Scleroderma ... , Systemic sclerosis ... differential #algorithm
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... an underlying cause ... frequently affected systems ... some time, let’s see ... As with many disease
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Evaluate for NMO, SLE ... Check Vitamin B12 ... • Infectious causes ... Disorders: - SLE ... Transverse Myelitis Treatment