18 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Autoimmune • ITP • SLE ... Quinidine • HIT ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... etc) - Viral: HIV ... - Nutritional: B12 ... - Autoimmune: SLE
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... test, ANA (e.g., SLE ... changes), high MCV anemia ... #Differential #Diagnosis ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... Associated - SLE ... • HCV, HBV Not ... #hematology #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - HIV • Immune ... immunodeficiency virus (HIV ... Treatment: ... #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Lupusreference #druginduced ... #table #rheumatology ... #diagnosis #management
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Causes of Pericardial ... - Differential Diagnosis ... Non-Infectious: • Rheumatologic ... : SLE, Rheumatoid ... #Causes #cardiology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... Check for IF ab Treatment ... consider IM or IV ... consider other diagnosis ... Cobalamin #Deficiency #diagnosis
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
enzymes ↑ • Mild anemia ... • New onset SLE ... for 10-12 days ... antibody test) Treatment ... #diagnosis
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Scl70 (in some cases ... , OJ, PL-7, PL-12 ... Rods/rings: - HCV ... #differential #diagnosis ... #rheumatology