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hematology diagnosis management differential algorithm doac leukemia malignancy anticoagulation chronic cll comparison lymphocytic mds myelodysplastic pharmacology testing vte workup abscess
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... telomeropathy Cancer ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Treatment of breast cancer: a simplified view surgical therapy - 5-7 weeks - lumpectomy + - radiation
Treatment of breast ... cancer: a simplified ... chemotherapy - 12 ... #treatment #management ... timeline #simplified #oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
particular degree of anemia ... Index < 2: • Anemia ... loss), Vitamin B12 ... infiltration (e.g. cancer ... Production #Index #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... of cancer-associated ... VTE #Malignancy #Cancer ... Anticoagulation #Management #Hematology ... #Oncology
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 Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
incidental DVT or PE in cancer ... thrombosis in cancer ... VTE #Malignancy #Cancer ... Anticoagulation #Management #Hematology ... #Oncology
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
metastases Treatment ... - Cytopenias (anemia ... differential #diagnosis #oncology ... #cancer #malignancy
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... - Parvovirus B19 ... • Parvovirus B19 ... Treatment: ... #oncology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Diagnosis #Algorithm #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
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