27 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... Iron deficiency anemia ... • Nephrotic syndrome ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Differential Diagnosis Algorithm ... - Low Serum B12 ... Myelodysplastic Syndromes ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Autoimmune Diseases: • Systemic ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... severe disease Treatment ... Summary #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Demyelinating syndromes ... ) Blood (75%): Anemia ... Thrombocytopenia #Lupus #SLE ... symptoms #diagnosis #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... immunosuppressive meds • +/- Anticoagulation ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus [SLE ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Differential #Diagnosis #Algorithm
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Differential Diagnosis Algorithm ... renal failure/uremia ... Myelodisplastic syndrome ... #generalized #dermatology ... Differential #Diagnosis #Algorithm