40 results
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Marrow Failure Syndromes ... with Pancytopenia ... Telemore Biology Disorders ... lauraebrown #Pancytopenia ... #diagnosis #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... , CKD • Hemolytic ... Folate deficiency, B12 ... #MCV #Algorithm ... Differential #Diagnosis #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Neutropenia with Pancytopenia ... Differential Diagnosis Algorithm ... Toxins • Aplastic Anemia ... deficiency: • B12 ... #Causes #Hematology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Hemolytic Anemia ... , Autoimmune disorder ... Spherocytes • Treatment ... • Treatment: Warm ... #Anemia #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
syndrome (ST-HUS ... crisis • Severe B12 ... anemia" • HELLP ... syndrome • Catastrophic ... differential #diagnosis #hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... anemia (MCV 80- ... a hematologic condition ... hemoglobin of less than 12 ... that involves disorders
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Reticulocytes, MCV ... Deficiency • B12 ... • RBC Membrane Disorder ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... • Bleeding • Hemolysis ... (>100 fL) • B12 ... #MCV #Classification ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Causes #Hematology