27 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
fragmentation hemolysis ... crisis • Severe B12 ... • Mechanical hemolysis ... anemia" • HELLP ... #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... Microangiopathic hemolytic ... purpura (TTP), Hemolytic ... differential #diagnosis #hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... purpura/hemolytic ... uremic syndrome ... , Hematology 2012 ... #Differential #Algorithm
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... reticulocytes • Hemolysis ... Antibody #Autoimmune #Hemolytic ... #management #treatment ... #rheumatology
Algorithm for the outpatient management of thrombocytopenia. 
(DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
Algorithm for the ... outpatient management ... acid; HELLP = hemolysis ... platelet count; HUS = hemolytic ... uremic syndrome
Autoimmune Hemolytic Anemia (AIHA) Treatment
Warm AIHA:
1) Steroids - 1-2 mg/kg prednisone daily
   • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... > 10, no more hemolysis ... AIHA #Autoimmune #Hemolytic ... Treatment #management
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Schistocytes, thrombocytopenia ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... #workup #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... -100): • Non-hemolytic ... , CKD • Hemolytic ... Folate deficiency, B12 ... Differential #Diagnosis #hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework
LOW RETIC INDEX - ↓ PRODUCTION
 • Vitamin
PRODUCTION • Vitamin B12 ... splenomegaly, Thrombocytopenia ... Destruction: Zieve's syndrome ... , Autoimmune hemolytic ... anemia, Hemolysis
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... uremic syndrome ... Thrombotic idiopathic thrombocytopenia ... #differential #hematology