52 results
diagnosis differential algorithm causes management classification rheumatology thrombocytosis workup dermatology mcv aplastic atlas cancer chronic cirrhosis cll hemolysis intravascular lymphocytic
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
• Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Cancer: • Leukemia ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
and non-hematologic ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency ... : • B12/folate ... Algorithm #Causes #Hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Algorithm - Iron deficiency ... anemia - Anemia ... disease - Vitamin B12 ... and/or folate deficiency ... Underproduction #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... effect following treatment ... malignancy • Iron deficiency ... anemia #Thrombocytosis ... Algorithm #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... transformation to acute leukemia ... only curative treatment ... #hematology #oncology
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic Anemia ... • 812, Folate ... Deficiency • ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
• Dietary Deficiency ... - Low Serum B12 ... Myelodysplastic Syndromes ... and Folate Deficiency ... Algorithm #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Megaloblastic: Vitamin B12 ... deficiency, Folate ... deficiency • ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... blood loss (Fe deficiency ... Chronic Myeloid Leukemia ... causes #Platelets #hematology
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