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management rheumatology dermatology causes algorithm systemic classification disease infectiousdiseases nephrology signs symptoms cancer emergencies erythematosus hemeonc leukemia lupus myelodysplastic pain
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... Headaches • Pale skin ... Treatment: ... #oncology #hematology ... #diagnosis #management
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Human parvovirus B19 ... • Rheumatic fever ... Antiphospholipid-antibody syndrome ... #rashes #differential ... #diagnosis #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic M - Malignancy: Leukemia cutis,
Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... dermatoses #skin ... #differential # ... diagnosis #cancer
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diagnosis Congenital ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... crisis • Severe B12 ... macroangiopathic hemolytic anemia ... " • HELLP syndrome ... #diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... morphologic #mcv #differential ... #hematology
Fever and Rash - Differential Diagnosis Framework • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - ... Differential Diagnosis ... HIV, Parvovirus B19 ... #Rash #Differential ... #Diagnosis #dermatology
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