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diagnosis causes algorithm rheumatology dermatology oncology classification hemolysis secondary signs symptoms disease mcv nutrition pruritus thrombocytosis atlas dress elevation erythematosus
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Bleed • Hemolysis ... • Early Iron Deficiency ... #Differential # ... Algorithm #Causes #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... crisis • Severe B12 ... deficiency • Mechanical ... hemolytic anemia ... #diagnosis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
↑ LDH • Anti-RBC ... • Blood smear: Differential ... FOR a cause → Systematic ... #management #treatment ... #rheumatology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
: Vitamin B12 or ... Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... #Morphology #differential ... #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Reticulocytes • Iron Deficiency ... • B12/Folate ... Deficiency • Aplastic ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... Myelodysplastic syndrome ... uremic syndrome ... key #diagnosis #differential ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... , CKD • Hemolytic ... Spherocytosis, G6PD, PK, HbC ... , B12 deficiency ... #Diagnosis #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
• Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Neutrophils - Low RBC ... RBCs in Rouleaux ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... • Intrinsic RBC ... G6PD deficiency) ... Extravascular #Causes #differential ... #diagnosis #hematology
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