96 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Low Serum B12 ... - Low Serum B12 ... Myelodysplastic Syndromes ... • Rule out B12 ... Algorithm #Causes #Hematology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Erythropoiesis (B12 ... in pernicious anemia ... • Refeeding syndrome ... Diagnosis #Algorithm #nephrology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
hemolytic-uremic syndrome ... crisis • Severe B12 ... macroangiopathic hemolytic anemia ... " • HELLP syndrome ... differential #diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Framework for Anemia ... thalassemia • Anemia ... Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... • Anterograde amnesia ... Therefore, Korsakoff Syndrome ... Encephalopathy Treatment ... #neurology #diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
Pharmacological Treatment ... of Hepatorenal Syndrome ... edgarvlermamd - Nephrology ... #HepatoRenal #Syndrome ... #Nephrology #Management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... - Parvovirus B19 ... • Parvovirus B19 ... Treatment: ... #oncology #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... vasculitis • Hematologic ... Abnormalities: macrocytic anemia ... criteria for 1) hematologic ... polyarteritis nodosa (12%