12 results
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
• Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Diseases: • Systemic lupus ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... • Anterograde amnesia ... presentation of Thiamine deficiency ... Encephalopathy Treatment ... #neurology #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... - Parvovirus B19 ... Treatment: ... #oncology #hematology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Anorexia nervosa Treatment ... Encephalopathy • A prompt treatment ... development of Korsakoff syndrome ... (chronic B1 deficiency ... Diagnosis #Management #neurology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Nutritional: DiabetesB12 deficiency ... , Uremia/ESRD, Hypothyroidism ... Vasculitis, Sjogren's, Lupus ... Paraprotein-associated (POEMS syndrome ... diagnosis #causes #neurology
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
- Thiamine Deficiency ... thiamine (vitamin B1 ... and retrograde amnesia ... #vitaminB1 #B1 # ... diagnosis #comparison #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... diagnosis #management #treatment
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
change disease • Hematologic ... malignancies Treatment ... Capillary leak syndrome ... #AKI #Cancer #Oncology ... Classification #Nephrology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... 0.5-0.7 g/g by 12 ... Nephritis #Management #treatment ... #management #rheumatology ... #nephrology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Nutritional: vitamin B12 ... or folic acid deficiency ... • Copper deficiency ... #diagnosis #hematology ... #oncology