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diagnosis management hematology differential lupus syndrome systemic causes erythematosus summary algorithm comparison dermatology infections table cardiology chemotherapy chronic classification cll
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Leukemia, Tumour ... Megakaryopoiesis • B12 ... Autoimmune • ITP • SLE ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... lymphocytic lymphoma (SLL ... Lymphocytic Lymphoma (SLL ... transformation of the CLL/SLL ... #Hematology #Oncology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... Cancer: • Leukemia ... and Autoimmune Diseases ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... cells can indicate disease ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
transformation to acute leukemia ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
dysmotility • MCTD (SLE ... • Specific for SLE ... Treatment: • ... Erythematosus #SLE ... Summary #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Human parvovirus B19 ... Malar rash • SLE ... infection • Lyme disease ... IBD • RA • SLE ... differential #diagnosis #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... transformation) Treatment ... chemotherapy for low-risk disease ... #oncology #hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g. celiac disease ... Advanced Liver Disease ... RA, SLE), Post-partum ... promyelocytic leukemia ... comparison #diagnosis #hematology
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Non-Infectious: • Rheumatologic ... : SLE, Rheumatoid ... : EGPA, Horton Disease ... , Takayasu Disease ... Primary: Lymphoma, Leukemia
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