30 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome • Clinically ... disorders • Diagnosis ... and Treatment Algorithm ... Syndrome #HES #Hematology ... #management #algorithm
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Treatment: ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
and initial management ... and to adjust treatment ... #Diagnosis #Management ... #Hematology #HIT ... Thrombocytopenia #Algorithm
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Differential Diaqnoses ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... for alternate diagnoses ... of AECOPD: • Clinical ... #COPD #AECOPD #Algorithm ... #treatment #pulmonary
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... inflammation, leading ... permeability Diagnosis ... CNS #neurology #rheumatology ... #management #treatment
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... increased IgG4+ cells ... " Treatment: ... #management #phenotypes ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology