46 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... (Chronic Myeloid ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... can indicate disease ... microglobulin Treatment ... leukemia #CLL ... #Leukemia #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... involved) • No leukemic ... Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... #oncology #diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... - History of Bleeding ... Age > 50 • Chronic ... Reed-Sternberg Cells ... #Differential #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... lymphocytes, smudge cells ... chemotherapy for low-risk disease ... #hematology #hemeonc
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... similarly to mast cells ... Disorders: • Chronic ... Colitis and Crohn’s Disease ... #causes #hematology
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
of autoimmune disease ... as pancytopenic/ill ... version DDx: - chronic ... morphologic/clinical disease ... hemepath #pathology #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Myelogenous Leukemia ... : • Acute or Chronic ... disorders • Celiac disease ... effect following treatment
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... , Bleeding gastric ... PD deficiency, Pulmonary ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
neutropenia • Mucosal bleeding ... Symptomatic anemia Diagnosis ... Consider stem cell ... to MDS or acute leukemia ... #hematology