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hematology oncology management anemia mds myelodysplastic algorithm cancer causes chronic cll coagulation dic differential disseminated hodgkins intravascular lymphocytic lymphoma myelodysplasia
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... to MDS or acute leukemia ... #Anemia #diagnosis ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... = funny-shaped cells ... transformation to acute leukemia ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... virus (EBV) • Leukemia ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Pure red cell aplasia ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... Treatment: ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... involved) • No leukemic ... Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... #oncology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... Causes • Anemia • Aplastic ... • Hairy Cell Leukemia ... Myelodysplastic #Syndromes #diagnosis
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
: 33% • Treatment ... , and CXR with pulmonary ... : No • Treatment ... #diagnosis #comparison ... #table
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... acute myeloid leukemia ... median age at diagnosis ... cardiovascular or pulmonary ... an infection or bleeding
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