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hematology management oncology differential algorithm causes classification hemeonc syndrome aplastic cell chronic disorders hodgkins lymphocytic lymphoma mds myelodysplastic workup abscess
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... night sweats, bleeding ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... • Neutropenia, anemia ... microglobulin Treatment ... leukemia #CLL ... #diagnosis #workup
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
neutropenia • Mucosal bleeding ... Treatment: • Consider ... stem cell transplant ... to MDS or acute leukemia ... #treatment #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
- Sickle cell anemia ... Liver diseases, Bleeding ... PD deficiency, Pulmonary ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... or λ), Smudge Cells ... Blood #Disorders #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... transformation to acute leukemia ... Allogeneic stem cell ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... minimal tumor burden Diagnosis ... lymphocytes, smudge cells ... 5) Symptoms of anemia ... #hemeonc #diagnosis
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
B-symptoms, bruising/bleeding ... hepatomegaly • Labs: anemia ... predominant immature cells ... #Algorithm #hematology ... #WBC #Leukemoid
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... Myelodysplastic #Syndromes #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... involved) • No leukemic ... Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... #oncology #diagnosis
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