38 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Malaise, bleeding ... -> AML: Blast crises ... fever, joint pain, bleeding ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Diagnosis: • ... microglobulin Treatment ... leukemia #CLL ... #diagnosis #workup ... #oncology #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... - Differential Diagnosis ... - History of Bleeding ... Reed-Sternberg Cells ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... transformation to acute leukemia ... Allogeneic stem cell ... #hematology #oncology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... similarly to mast cells ... Chickenpox Other Causes ... #Differential #Diagnosis ... #causes #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... by bleeding (petechiae ... Leukemia • Idiopathic ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
Massive Hemoptysis - Diagnosis and Management
 • Definitions: 
   - Hemoptysis = bleeding from
Massive Hemoptysis - Diagnosis ... has potential to cause ... • Workup • General ... #Management #treatment ... #workup #pulmonary
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
neutropenia • Mucosal bleeding ... Symptomatic anemia Diagnosis ... Consider stem cell ... to MDS or acute leukemia ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... not required in all ... #Causes #Workup ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... involved) • No leukemic ... Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... #oncology #diagnosis