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hematology management clinical differential algorithm lymphangioleiomyomatosis causes cxr hodgkins leukemia lymphoma pneumothorax radiologyassistant syndrome abscess anemia aplastic biopsy cancer cardiology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... activity • ↓ LAP ... night sweats, bleeding ... #Leukemia #Hematology ... #Oncology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... #hematology #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Leukemia - History of Bleeding ... Reed-Sternberg Cells ... Lymphadenopathy #LAD ... #Oncology
There is a hydropneumothorax. Notice the air-fluid level (blue arrow). The upper lobe is still attached to the
attached to the chest ... is a possible diagnosis ... small airways leading ... to pulmonary cyst ... #Clinical #Radiology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
suspected) - CT chest ... Simultaneous clotting and bleeding ... interventional radiology ... renal failure, pulmonary ... #HemeOnc #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... factor (GCSF) treatments ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
underarms, or chest ... Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... microglobulin Treatment ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... number of CD34+ cells ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... • Large volume feeding ... CXR upright or lat ... hemorrhage • Treatment ... Lung #Abscess #pulmonary
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