16 results
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... #treatment #medications ... #table #pharmacotherapy ... #decisionaid #cardiology ... #hematology #warfarin
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... - pulmonary opacities ... #management #hematology ... #oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... night sweats, bleeding ... manifestations, hypoxia, CXR ... #Leukemia #Hematology ... #Oncology #Diagnosis
Differential diagnosis
The table summarizes the most common diseases, that present with consolidation.
Chronic diseases are indicated in
The table summarizes ... - Cells - tumor ... respond to the treatment ... #Diagnosis #Radiology ... #Pulmonary #CXR
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Large volume feeding ... Blood cultures • CXR ... early disease) • CXR ... shows a small, stable ... Lung #Abscess #pulmonary
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
ecchymoses, mucosal bleeding ... number of CD34+ cells ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
involvement - seeding ... Tuberculosis Diagnosis ... and Culture • CXR ... disease • Check CXR ... Tuberculosis #TB #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... factor (GCSF) treatments ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology