26 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... bruising • Skin ... factor VIII) Treatment ... VonWillebrand #Disease #Diagnosis ... #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... management #algorithm #pharmacology ... #treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
anemia • Sickle cells ... Liver diseases, Bleeding ... PD deficiency, Pulmonary ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... glucocorticoid treatment ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Schistocytes, helmet cells ... Treatment: ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... Chemotherapy #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... night sweats, bleeding ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
- Differential Diagnosis ... lymphocytes, plasma cells ... the mainstay of treatment ... #comparison #table ... #dermatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... , and CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... ecchymoses, mucosal bleeding ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management