28 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Petechiae, bruising, bleeding ... manifestations, hypoxia, CXR ... • Significant bleeding ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
or basket cells ... can indicate disease ... microglobulin Treatment ... leukemia #CLL ... workup #oncology #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
involved) • No leukemic ... cells, natural ... Hepatosplenomegaly, cytopenias(bleeding ... Lymphomas • Other hematologic ... #differential #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... - Sickle cell anemia ... , Bleeding gastric ... PD deficiency, Pulmonary ... #differential #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
neutropenia • Mucosal bleeding ... megaloblastic anemia Treatment ... Consider stem cell ... to MDS or acute leukemia ... #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
total white blood cell ... similarly to mast cells ... Chronic myeloid leukemia ... Colitis and Crohn’s Disease ... Diagnosis #causes #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
(CLL) - Summary ... lymphocytes, smudge cells ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... transformation to acute leukemia ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Sickle Cell Disease ... Pathophysiology of disease ... membrane damage leading ... the sickle red cells ... Complications #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... • Severe Liver Disease ... Treatment: ... diagnosis #causes #treatment ... #management #hematology