14 results
diagnosis hematology management differential algorithm cardiology mds myelodysplastic syndromes anemia aplastic cancer cell chf chronic clinical cll criticalcare dermatology differentiation
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... : Blast crises ... smear: Blasts APML ... • Tumor lysis syndrome ... #Hematology #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... unusual bruising or bleeding ... by bleeding (petechiae ... • Hairy Cell Leukemia ... diagnosis #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Diagnosis: >3 symptoms ... management #hematology #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Simultaneous clotting and bleeding ... Treat underlying cause ... interventional radiology ... Usually myeloid leukemias ... renal failure, pulmonary
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... microglobulin Treatment ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... old, ~10,000 new cases ... transformation to acute leukemia ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... virus (EBV) • Leukemia ... • Improve the symptoms ... Aplastic #Anemia #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs and Symptoms ... development of skin symptoms ... Causes: - Idiopathic ... Treatment: - Systemic ... #dermatology #oncology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... or serologies + symptoms ... Goodpasture's cause ... leading to diffuse ... diagnosis #management #treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... increase in CD4+ cells ... Lymphadenitis, pulmonary ... leukoencephalopathy (PML ... #Inflammatory #Syndrome
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