49 results
Von Willebrand Disease - Clinical Presentation, Diagnosis and Management

- Dr. Eric Strong @DrEricStrong - Strong Medicine
Von Willebrand Disease ... - Clinical Presentation ... , Diagnosis and ... Diagnosis #Management #hematology ... #treatment
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
fibrillation) and ... validated for VTE treatment ... for prophylaxis and ... studies suggest net clinical ... Anticoagulation #Factors #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Acute bacterial and ... Diagnosis #Algorithm #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis and ... screening for disease ... with established disease ... by a hemophilia treatment ... #hematology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
pain, jaundice and ... Supportive with treatment ... , hepatomegaly and ... Hepatobiliary #hepatology ... #hepatitis #differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Thrombocytopenia and ... Platelet Disorders - Differential ... Diagnosis and Workup ... - History of bleeding ... Causes #Workup #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Syndrome - Diagnosis and ... thrombocythemia), Autoimmune disease ... cancer cells (and ... Diagnosis #Management #treatment ... #hematology #differential
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Increased Clotting and ... factors VII, X, V and ... organ damage Clinical ... (Hypersplenism and ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
, such as IL-1 and ... hemophagocytosis and ... Hepatosplenomegaly and ... • Heart, lung, and ... Diagnosis #Management #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphomas and Lymphoproliferative ... untreated, Behave and ... and relapse ... Amy Chung, MD, MSc ... pathophysiology #Hematology