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diagnosis rheumatology sle management causes systemic dermatology skinrash activation cerebritis clues comparison diffuse druginduced lad lymphadenopathy macrophage mas neurology oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus ( ... SLE) Clinical ... inflammation, leading ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... and CNS • Headache ... vein thrombosis Hematologic
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Diagnosis Algorithm ... • Systemic Lupus ... Erythematosus ... Leukemia - History of Bleeding ... #Causes #Hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... life-threatening • Treatment ... #Systemic #Erythematosus
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Vesiculobullous Skin Rash ... - Differential ... Diagnosis Algorithm ... Bullous systemic lupus ... erythematous
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin Rash ... - Differential ... Diagnosis Algorithm ... Erythrematous ... soles • Discoid Lupus
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... the face (many differential ... 3) Limb oedema leading ... clues #system #erythematosus ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
nervous system (CNS ... purpura to mucosal bleeding ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Erythematosus ( ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash
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