16 results
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... the face (many differential ... 3) Limb oedema leading ... 6) An annular rash ... erythematosus #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... SJIA], systemic lupus ... thrombocytopenia • Liver ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... inhibitor and lupus ... Willebrand syndrome • Lupus ... discern these causes ... #Diagnosis #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... inflammation, leading ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... disease: > 2 • NASH ... RBC (hemolysis, bleeding ... injury #hepatitis #differential
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... DIC • Severe Liver ... Treat primary cause ... #treatment #management ... #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... infiltration) Differential ... Maternal Support - Critical ... #Pregnancy #hepatology ... obgyn #diagnosis #management
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... AI, thyroid dz liver ... Classification #diagnosis #management ... #criticalcare #differential ... #causes #classification