51 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Antiphospholipid-antibody syndrome ... #skin #rashes #differential ... #diagnosis #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Kawasaki, Nephrotic syndrome ... Acute bacterial and ... Diagnosis #Algorithm #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... • Immunologic Workup ... : - ANA > ... Management #Summary #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... - History of bleeding ... function test, ANA ... (e.g., SLE), anti-phospholipid ... #hematology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... ), Sjogren's Syndrome ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Petechial or purpuric rash ... erythematosus [SLE ... Diagnosis #Management #Hematology ... #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... • Immunologic Workup ... • Immunologic Workup ... comparison #table #rheumatology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... HLH syndrome 5. ... #Differential # ... Diagnosis #Algorithm #Hematology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... including heliotrope rash ... anti-synthetase syndrome ... Can also see mechanics ... Myositis #diagnosis #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... the face (many differential ... 3) Limb oedema leading ... annular rash on ... erythematosus #rheumatology