27 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... - History of bleeding ... : INR/PT, aPTT(liver ... #Diagnosis #Causes ... #Workup #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Hemolysis, Elevated Liver ... child * Severe cases ... exchange 2) Fatty liver ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... Iatrogenic) • Liver ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... 80-100 fL) • Bleeding ... #Causes #Hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Diagnosis Hepatocellular ... Toxic: Medication, Pregnancy ... #Diagnosis #Causes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... Pregnancy) - Low ... #Causes #Hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Pregnancy Intrahepatic ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential # ... diagnosis #icp #
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Wilson's • Pregnancy ... #Causes
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... = nonspecific (nausea ... infiltration) Differential ... Diagnosis: Viral ... #Pregnancy #hepatology