15 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Injury ... more specific for hepatic ... Transaminitis #diagnosis ... #differential # ... hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... Diagnosis Framework ... injury) • Ischemic ... ) • Non-hepatic ... #Diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... Vasculature • Hepatic ... #Injury #Differential ... #Diagnosis #Causes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Injury: • Hepatic ... RBC (hemolysis, bleeding ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... non-essential drug/HDS treatments ... disease, Hepatic ... #Injury #Diagnosis ... #Algorithm #hepatology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Acute sickle cell hepatic ... Supportive with treatment ... Hepatobiliary #hepatology ... #hepatitis #differential ... #diagnosis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
replaced by non-hepatic ... RBC (hemolysis, bleeding ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... Treatment: ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
change disease • Hematologic ... malignancies Treatment ... depletion • Hepatic ... Cancer #Oncology #Differential ... #Diagnosis #Classification
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... Acquired: • Heparin ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology