16 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... ) - Differential ... 80-100 fL) • Bleeding ... #MCV #Classification ... Algorithm #Causes #Hematology
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Pregnancy, EPO treatment ... Loss (without anaemia ... Hookworm infection, Bleeding ... Iron #Deficiency #differential ... diagnosis #causes #nutrition
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Reticulocytes, MCV ... Disease • Marrow ... #Classification ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... telomeropathy Cancer ... Antibody-mediated hemolysis Nutritional ... #Diagnosis #Hematology
Causes of Iron Deficiency
 • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Celiac, Enteritis, Bleeding ... : Gl lesions / cancer ... : IBD, Chronic disease ... #diagnosis #anemia ... #nutrition
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... - History of bleeding ... epistaxis, gingival bleeding ... PT, aPTT(liver disease ... anemia (vegan,
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Vasculitides, IBD, Celiac disease
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
LC deposition disease ... • Hematologic ... malignancies Treatment ... #Oncology #Differential ... #Diagnosis #Classification
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... HBV, Coxsackie, CMV ... hemopathies, solid cancers ... diagnosis #management #treatment ... #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
HIV, EN, HTLV-1, HCV ... translocation • Types: Classification ... Hepatosplenomegaly, cytopenias(bleeding ... involvement Differential ... #hematology